Inhibition of the acid lipase activity by apolipoprotein A-I in the presence of lysosomal proteases.
نویسندگان
چکیده
It was found that the inhibition of the lysosomal acid lipase activity by rat apolipoprotein A-I (apo A-I) was increased with the degradation of apo A-I by the lysosomal proteases. We demonstrated that apo A-I could effectively inhibit the acid lipase activity even in the presence of the lysosomal proteases using the hepatic lysosomal fraction.
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عنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 63 5 شماره
صفحات -
تاریخ انتشار 1999